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December 2007

Features

Cover Story

Cancer Vaccines: A Century in the Making... Almost Here?

Cancer immunotherapeutics, including vaccines, may hit the market by the end of this decade. They promise longer survival and perhaps indefinite remission at a more favorable cost-benefit ratio than that of oncologics now in use. They also may fuel dramatic changes in how healthcare is delivered and financed.
Katherine T. Adams
PDF

Business

Convergence in the Midst of Competition

As biotechs hit their adolescence, they — like test makers and pharmaceutical manufacturers — are more likely than ever to reach outside of their own areas of expertise, link hands with the other guys, and pursue new programs and technologies.
John Carroll
PDF

Policy

Biopharmaceuticals: The Economic Equation

As more biopharmaceuticals reach the market, more attention will be given to issues such as cost-effectiveness evaluations, biosimilars, and price controls. The value ­biologic therapies bring to the healthcare system may take years to ­appreciate in full — perhaps only when policy decisions allow for their economic effects to be understood.
Erwin A. Blackstone, PhD, and Joseph P. Fuhr Jr., PhD
PDF

Diagnostics

A Wish List for Molecular Tests

Companion diagnostics improve health outcomes, say developers, who are willing to work with payers to develop medical policies for coverage. Payers and clinicians want more evidence of long-term benefit. The FDA, meanwhile, is jostling for regulatory control. How long will patients have to wait? Part 2 of 2
Bob Carlson, MHA
PDF

Regulatory

Lower Cost and Faster Product Approval Through Proper Software Design Controls

The market success of a medical device depends in large part on how well its software is programmed. Focusing heavily on the device while treating the software as an afterthought can lead to costly recalls and liability concerns.
Kevin Stevens and Anthony Johnson
PDF

Departments

Openers

Some Predictions for 2008

Looking ahead to 2008.
Michael D. Dalzell
PDF

Editorial

The Biotech Detail Rep of the Future

David B. Nash, MD, MBA, on the detail rep of tomorrow.
David B. Nash, MD, MBA
PDF

Washington Watch

Money-Back Guarantees: Where Private Payers Might Not Wait for CMS To Lead

Pay for performance, pharma style.
John Carroll
PDF

Diagnostics and Devices

Ousting the ‘Ouch Factor’ in Drug Delivery

Pointers on perfecting drug delivery.
Bob Carlson, MHA
PDF

DrugTrack

Approvals, FDA Actions, Clinical Trials

FDA approvals and other actions, plus results of key clinical trials.
Bob Carlson, MHA
PDF

Biotech Business

Employers Work To Manage Biologics in 2008 Benefit Designs

Benefit designs for 2008.
Amanda Brower
PDF

Conference Coverage

Making an Impression on Biotech Development

Life imitates art.
Neil Versel
PDF

Trends: Specialty Pharmacy

Additional Indications Drive Higher Specialty Spending

Multiple indications boost SP spending.
Amy Krajacic
PDF