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December 2005

Features

Cover Story

Gene-Based Diagnostics: Ready for Prime Time?

With so many tests in development, health care is preparing for a rush of changes with far-reaching effects. Diseases will be detected earlier and responses to drugs and treatment will be more predictable. Evidence of their effectiveness will dictate their acceptance.
Katherine T. Adams
PDF

Devices

Nanotechnology: What's in It for Biotech?

Speculation is high about a technology that promises reduced medical costs and better outcomes through more efficient drug discovery, disease detection, and drug delivery.
John Mack
PDF

Medicare

8 Lessons Health Plans Learned From Participating in Part D

Health plans and manufacturers are scrambling toward the last great untapped market: Medicare. Getting there has been, well, half the fun.
Lola Butcher
PDF

Business

The Stealth Emergence of Contract Research Organizations

Quickly and quietly, CROs have come to dominate the drug-testing arena. Clinical-trial recruitment and enrollment will never be the same.
John Carroll
PDF

Economics

Getting Discovery to the Commercial Arena: Not for the Faint of Heart

Moving a new idea to market is a tenuous process that demands balance between investors and inventors and careful management of financial risk.
Carolyn d’Arville, PhD
PDF

Leading Edge

Does Race Have a Place In Biotechnological Research?

Controversy is exploding, and implications are surfacing with the FDA’s approval of a drug that presumes genetic differences between whites and blacks
Jack McCain
PDF

Departments

Openers

So Many Topics... So Little Space

Some year-end food for thought.
Michael D. Dalzell
PDF

Editorial

Public Health Genomics

David B. Nash, MD, MBA, demurs on genomics and population health.
David B. Nash, MD, MBA
PDF

Washington Watch

Pharmacovigilance: The New Drug-Development Standard

Pharmacovigilance equals a higher premium on risk management.
John Carroll
PDF

DrugTrack

Approvals, FDA Actions, Clinical Trials

Bob Carlson
PDF

Diagnostics and Devices

Task Force Breaks New Ground with Breast Cancer Recommendations

U.S. weighs evidence for genetic testing and counseling for breast cancer risk.
Bob Carlson
PDF

Biotech Business

Specialty Drug Costs Continue To Rise; Employees Hit With Higher Premiums

Cost sharing on the rise as consumers pay a higher percentage of drug costs.
Amanda Brower
PDF

Pipeline

High-deductible Health Plans Must Account For Increased Specialty Drug Use

Benefit design evolves for specialty drugs.
Katherine T. Adams
PDF