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July/August 2004

Features

Leading Edge

Pharmacogenomics: Where Will It Take Us?

Until now, drug research has focused on developing blockbusters to treat millions of people. Pharmaco-genomics works from the inside out: Researchers use genetic information to interpret disease pathways and create drugs for small, likely-to-respond populations. How it affects payers and patients.
Linda Hull Felcone
PDF

Benefit Design

Biotech Injectable Drugs: Clinical Applications and Financial Effects

Biotech injectables rarely fit traditional drug benefit designs, potentially undermining a health plan’s goals. The authors, employee-benefit consultants, present actuarial models.
F. Randy Vogenberg, RPh, PhD, and Coleen Young, FSA
PDF

Business

Follow the Money: How Biotech’s Funding Shapes Its Direction

Which source of funding – venture capitalists or pharmaceutical makers – provides the most innovative and useful path for a small biotech company?
Ed Silverman
PDF

Specialty Pharmacy: New Guise for an Old Feud?

Some specialists depend on the markup on injectables. To contain costs, health plans move control of biologic distribution from physicians to specialty pharmacies. Welcome back to the plan-provider turf wars of the ’90s.
Neil Versel
PDF

Reimportation and Biotech: A Germinating Crisis?

Reimportation doesn’t pose a safety threat only with traditional drugs. There’s profit potential – and danger – in counterfeit biologics.
Chuck Appleby
PDF

Clinical Focus

Targeted IgE Therapy for Patients With Moderate to Severe Asthma

Bradley E. Chipps, MD, and Patricia L. Marshik, PharmD, review the clinical benefits of IgE-blocker therapy and who stands to benefit from it.
Bradley E. Chipps, MD, and Patricia L. Marshik, PharmD
PDF

Departments

Editor's Memo

Objects in Our Mirror Are Closer Than They Appear

Michael D. Dalzell
PDF

Editorial

Pharmacogenomics and “Pharmacoecogenomics”

David B. Nash, MD, MBA
PDF

Drugs and Diagnostics

Biomarkers Gain Prominence In Drug Discovery and Development

Bob Carlson
PDF

Discourse: Regulatory

Government Pushes To Oversee Potential Recipes for Bioterrorism

Feds seek controls on publishing a virtual how-to for bioterrorists.
John Carroll
PDF

Biotech Business

E&Y: Productivity Will Move Biotechs to Profitability

New report sees profitability in biotech industry by 2008.
Amanda Brower
PDF

In the Pipeline

Biotech Pipeline Set For Future Sales Growth

Biotech pipeline thrives, setting stage for future sales growth.
Amanda Brower
PDF